http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113248384-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2603-38 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-732 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C49-737 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-78 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-235 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-231 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-737 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-732 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-122 |
filingDate | 2021-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113248384-B |
titleOfInvention | Diterpenoid compound and its preparation method and use |
abstract | The invention discloses a diterpenoid compound, a preparation method and application thereof, and belongs to the technical field of medicine. First, the varnish is extracted with an aqueous ethanol solution to obtain a crude extract, and then successively extracted with an organic solvent, ODS chromatographic column, and HPLC chromatographic multi-stage separation to obtain a diterpenoid compound, the preparation of the diterpane compound of the present invention The method is simple, easy to operate, and convenient for industrial scale-up production. The diterpenoid compound prepared by the invention has significant cytotoxicity to drug-resistant cell line A549/Taxol, and is expected to be used as a potential drug for drug-resistant lung cancer treatment. |
priorityDate | 2021-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 81.