http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113248384-B

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filingDate 2021-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113248384-B
titleOfInvention Diterpenoid compound and its preparation method and use
abstract The invention discloses a diterpenoid compound, a preparation method and application thereof, and belongs to the technical field of medicine. First, the varnish is extracted with an aqueous ethanol solution to obtain a crude extract, and then successively extracted with an organic solvent, ODS chromatographic column, and HPLC chromatographic multi-stage separation to obtain a diterpenoid compound, the preparation of the diterpane compound of the present invention The method is simple, easy to operate, and convenient for industrial scale-up production. The diterpenoid compound prepared by the invention has significant cytotoxicity to drug-resistant cell line A549/Taxol, and is expected to be used as a potential drug for drug-resistant lung cancer treatment.
priorityDate 2021-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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