http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113244234-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-222 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-444 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-444 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-222 |
| filingDate | 2021-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113244234-B |
| titleOfInvention | Aureoamidol ester-barbaloin-palmitate self-assembled nanoparticles and preparation method and application thereof |
| abstract | The invention discloses a self-assembled nanoparticle of aurora ester-barbaloin-palmitate, which is characterized in that: the self-assembly nanoparticle is formed by self-assembly of aureoamide alcohol ester, barbaloin and palmitate. The self-assembled nanoparticles have an average particle size of about 150nm, are uniformly distributed in a similar spherical shape, and have narrow particle size distribution range and high stability. The invention also discloses a preparation method of the self-assembled nanoparticles, which comprises the following steps: dissolving aureamide alcohol ester, barbaloin and palmitate in a benign organic solvent to form a mixed solution; and dropwise adding the mixed solution into pure water with the constant temperature of 60-70 ℃, stirring, and dialyzing to remove the organic solvent. In vitro cytotoxicity experiments show that the self-assembled nanoparticles obviously inhibit the proliferation of cells of liver cancer, lung cancer and breast cancer. The invention also discloses the application of the self-assembled nanoparticles in preparing anticancer drugs. |
| priorityDate | 2021-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.