http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113237902-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e42017660582c8e308dd858fa167dd5c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N23-046 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N23-046 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-02 |
| filingDate | 2021-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72310df312f1e3d80f9c1d48e279523b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_147b8c2546ba25b36142dc07a357fe30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ebe024d779f904c9323f8b13f87f53b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0901206efcbc6125b80aa8d2c6cce9a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_611fd208339ab099c6f5b17c39f6d6c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f7e4a01d5606db64b11890e74b77623 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51620a3850c6ae147a7d2f990e051d66 |
| publicationDate | 2021-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113237902-A |
| titleOfInvention | Method for establishing tree shrew periodontitis model |
| abstract | The invention discloses a method for establishing a tree shrew periodontitis model, which comprises the following steps: (1) selecting adult healthy male tree shrews for modeling, wherein the weight of the male tree shrews is 130-200 g; dividing 40 tree shrews into a normal control group and an experimental group by adopting a random control method, observing for 1-8 weeks, and each group has 3-8 tree shrews per time point; performing no treatment on the control group, and performing silk thread ligation on the first molars of the right mandible of all the rest tree shrews by using 2-0 silk threads; (2) observing and recording clinical manifestations of the tree shrews at the ligation positions 1-8 weeks after ligation, killing the tree shrews, and collecting mandibles of the tree shrews; (3) Micro-CT scanning is used for detecting bone tissue absorption degree, HE staining is used for detecting inflammatory cell infiltration degree of periodontal tissue, TRAP staining is used for detecting osteoclast infiltration degree quantity, and IHC staining is used for detecting inflammation related proteins TNF-alpha, IL-1 alpha, MPO and osteoclast related protein Cathepsin K expression conditions. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113841658-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114699202-A |
| priorityDate | 2021-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.