| abstract |
The invention relates to an 'wettability' total coumarin, a preparation method and a medicinal application thereof, belonging to the field of preparation of effective ingredients of traditional Chinese medicines and natural medicinal chemistry. Air drying the flakes, pulverizing, sieving with 20-40 mesh sieve, weighing, and adding into supercritical CO 2 And extracting in an extraction device. The invention has the advantages that the effective part with anti-inflammatory effect is extracted and enriched from the break for the first time: total coumarins; the preparation method of the extract is simple, green and environment-friendly, and is suitable for industrial production; the extract has pharmacological effects of remarkably relieving inflammatory reaction of animal with osteoarthropathy, inhibiting chondrocyte apoptosis, promoting chondrocyte proliferation, and remarkably relieving pathological injury of joint soft, and can be used for preparing medicineVarious medicines or health foods with anti-osteoarthritis effect. |