| abstract |
The present invention relates to antibody-drug conjugates comprising: (i) an antibody or antigen-binding fragment thereof, (ii) a polymer comprising specific repeat units, optionally covalently bound by a linker to one or more biologically active moieties, such as a small molecule drug, and (iii) a polymer-antibody linker moiety, covalently bound to both the polymer and the antibody or antigen-binding fragment thereof. Furthermore, the present invention relates to pharmaceutical compositions comprising the antibody-drug conjugates and to the use of the antibody-drug conjugates in medicine. |