| abstract |
The invention discloses a method for improving the in vitro maturation and development rate of porcine oocytes by using agomelatine, in particular, a method for using the melatonin receptor agonist agomelatine to improve the in vitro maturation and development rate of porcine oocytes. Porcine cumulus cell expansion, oocyte in vitro maturation (IVM), oocyte development-related gene expression, and parthenogenetic embryo development ability were significantly improved. |