http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113214232-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 |
filingDate | 2021-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113214232-B |
titleOfInvention | A kind of coelenterazine PBI 3939 intermediate and preparation method thereof |
abstract | The invention discloses a method for preparing an important intermediate of novel coelenterazine Furimazine (PBI 3939). (Dimethylamino)-3-(furan-2-yl) ethyl acrylate, then, 2-(dimethylamino)-3-(furan-2-yl) ethyl acrylate undergoes hydrolysis reaction to obtain 3-( Furan-2-yl)-2-oxopropionate ethyl ester, finally, 3-(furan-2-yl)-2-oxopropionate ethyl ester and 2-amino-3-benzyl-5-phenyl The intermediate is prepared by the pyrazine reaction. The raw materials of the invention are cheap and easy to obtain, the reaction conditions are mild and easy to control, the cost is low, the industrialization is easy to be realized, the production capacity is large, and the obtained product has high purity and stable quality. |
priorityDate | 2021-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.