http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113214164-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7ed2c6ea50a4987af16b0ae112562f5a |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-36 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-36 |
filingDate | 2021-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_431b2bd83180c6676aa6996668c204a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7f146d4b20bb1fc650e790a98c2c180 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a29a1992e420866d18f3cd5d3abc1d8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f6f51fbdb99e823a0d4cb407f944754 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8919f3640de7395bfc113c044e08e2a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bda88a1cfea5b3a17dec072a5e18c22f |
publicationDate | 2021-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113214164-A |
titleOfInvention | A kind of synthetic method of leberoxine intermediate 2,4-dimethylpyrimidine-5-ol |
abstract | The invention discloses a method for synthesizing 2,4-dimethylpyrimidine-5-alcohol, an intermediate of Lebron, aiming to solve the safety risk of industrial production of 2,4-dimethylpyrimidine-5-alcohol and serious environmental pollution. The present invention takes benzoic acid as the starting material, firstly carries out esterification reaction with chloroacetone; then carries out alkylation reaction and ring closure reaction with N,N-dimethylformamide dimethyl acetal and acetamidine hydrochloride; finally 2,4-dimethylpyrimidine-5-alcohol is obtained by de-benzoic acid hydrolysis reaction. The method uses benzoic acid, which widely exists in nature, as the main raw material, and solves the health problems caused in the production. %"The advantages. |
priorityDate | 2021-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 117.