http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113209377-A

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filingDate 2021-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4766d92e62c1b04386ee9836e83e320a
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publicationDate 2021-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113209377-A
titleOfInvention A kind of silk fibroin/silica composite material and preparation method thereof
abstract The invention discloses a preparation method of silk fibroin/silica composite material, which comprises the following steps: (1) preparation of silica sol: mixing tetraethyl orthosilicate and water, adding silk fibroin solution, Then, ethanol is added to adjust the pH value of the system to 2 to 3, then the temperature is raised to 50 °C to 70 °C, and the reaction is stirred to obtain silica sol; (2) Preparation of composite solution: The silica sol is cooled to room temperature, and the silk fibroin solution is added to the silica sol while stirring to obtain a composite solution; (3) Preparation of gel: Pour the composite solution into a mold, and heat the solution at 30°C to 50°C. (4) After the gel in step (3) is purified, aged, dried and dehydrated, the silk fibroin/silica composite material is obtained. According to the preparation method of the silk fibroin/silica composite material of the present invention, the prepared SF/SiO 2 composite material has excellent mechanical properties and good biocompatibility.
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Total number of triples: 38.