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filingDate 2021-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06a7820d60ab34330bd4bf2b3750fc47
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publicationDate 2021-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113201530-A
titleOfInvention Method for removing phage expressing carrier protein Nanobodies from a hapten phage-displayed Nanobody library
abstract The invention discloses a method for removing phage expressing carrier protein nanobody in a hapten phage display nanobody library. The method comprises (1) incubating the magnetic beads coupled to the carrier protein with the hapten phage-displayed nanobody library to obtain magnetic beads that bind the phage expressing the carrier protein nanobodies; (2) removing all the magnetic beads by magnetic separation. The magnetic beads that bind to the phage expressing the carrier protein Nanobody, thereby removing the phage expressing the carrier protein Nanobody in the hapten phage display Nanobody library. This method improves the screening efficiency of small molecule nanobodies.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114524774-A
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