http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113200980-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_900294f396b66b4694648daa18c8a4c8 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-584 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
filingDate | 2021-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05792d75d1b2007c451f4d3c480d494b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c58fd6146dc10b0fb673bcd1690de142 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ecc6464338bfa54b515ea6f41d8ed92f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04bf4480d512ba9c4f37b193fca6373c |
publicationDate | 2021-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113200980-A |
titleOfInvention | A kind of method of silver-catalyzed synthesis of indolizine compounds |
abstract | The invention discloses a method for synthesizing indolizine compounds catalyzed by silver. In an organic solvent system, N-benzoylmethyl pyridinium bromide represented by formula (1) and The isocyanide compound is a raw material, and the molar ratio of the two is 1: (1.2-2.0), and the metal silver salt is used as a catalyst. After post-treatment, the indolizine compound represented by formula (3) is obtained. The method has the advantages of simple operation, easily available raw materials and reagents, mild reaction conditions, green reaction system, easy separation and purification of products, and yield of up to 91%, and is suitable for the efficient and high-yield preparation of indolizine compounds, especially for synthesis Various 1,2-substituted indolizines. The invention is suitable for large-scale industrial production, and has wide application prospects and important significance in organic synthesis. |
priorityDate | 2021-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 82.