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filingDate 2021-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e70f1069581835cec1390cf3d79e54c5
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publicationDate 2021-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113200940-A
titleOfInvention Abeta plaque response type fluorescent probe and preparation and application thereof
abstract The invention provides an Abeta plaque response type fluorescent probe and preparation and application thereof, and relates to the technical field of design synthesis and application of response type fluorescent probes. The A beta plaque response type fluorescent probe is mainly prepared by condensation reaction of a product obtained by methylation reaction of methylbenzothiazole and methyl iodide and 4-hydroxy-2-methoxybenzaldehyde. The invention overcomes the defects of the prior art, the synthetic route of the probe is simple, the operability is strong, and the target probe has good water solubility and biocompatibility, thereby providing potential application value for diagnosing and treating diseases related to A beta protein abnormality, particularly AD.
priorityDate 2021-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 44.