http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113200926-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53b4d53983adbf56dd0e7d0bf96f8ce5 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-91 |
| filingDate | 2021-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fa6f37877c097c245ac561720c30309 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52882dfe8b740cd6914326903641ed20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_233fa1273bfea50f51cb2604d5477f9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2eff480635b032527dd7e3ff47ac593d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a810dbc4fc83142cf1cdc9bdfc64659e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4458c5827d404f6bd5bb708d18e9488b |
| publicationDate | 2021-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113200926-A |
| titleOfInvention | A kind of method for modifying 2-arylquinazoline-4(3H)-one compounds |
| abstract | The invention discloses a method for modifying 2-arylquinazoline-4 (3H) -ketone compounds with diaryldifluorocyclopropene, which is used for synthesizing two kinds of 2-arylquinazoline-4(3 H )-ketone skeleton. In the present invention, 2-arylquinazoline-4( 3H )-ketones and diaryldifluorocyclopropenes are used as raw materials, and under the assistance of silver salt or silver salt and acid, carbon catalyzed by transition metal Efficient construction of 2-(2-(2-arylindan-1-alcohol)aryl)quinazolinone or cyclopentadienespiropyrrolo[1,2-b]quinazolinone structures by hydrogen activation reaction . Compared with the traditional synthesis method, the advantages of this method are as follows: (1) The substrate is suitable for a wide range and the product yield is high. (2) The three-component efficient synthesis of various quinazolinone derivatives is realized by one-pot method, the operation steps are simple, the pre-activation of the substrate is not required, and the post-treatment is convenient. (3) As a new coupling reagent, diaryldifluorocyclopropenes have the characteristics of simple synthesis method and high activity. (4) The reaction can be amplified at the gram level, which has potential application value. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115181014-A |
| priorityDate | 2021-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 116.