| abstract |
The invention provides an anthranilamide compound based on vorinostat skeleton and its preparation and application. The structural formula of the anthranilamide compounds based on the vorinostat skeleton of the present invention is: , wherein, n=1~6; R is methylamino, dimethylamino, hydroxyl, NH 2 or . The anthranilamide compound based on the vorinostat skeleton has the effect of inhibiting the proliferation of gastric cancer cells as determined by the MTT method, and can be used for preparing an anti-gastric cancer drug. |