| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e071d18fea054bf8d1420d483e78ed1 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3231
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-07052
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-322
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-321 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1282
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1241 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 |
| filingDate |
2019-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d27377178566a87a33a0849c77f8b203
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07422293c47872d65cae4f1e00782677
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e1c083e6431a29009aa0e524823d61a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a2691c39e3d578a54f64f0478e24e16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbf0be115b5bbf64cccd0825e0ea70d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bf0d9b10ff611075cbd14a0793a7996 |
| publicationDate |
2021-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-113195720-A |
| titleOfInvention |
Enzymatic RNA Synthesis |
| abstract |
The present invention describes methods for the controlled de novo synthesis of RNA oligonucleotides using enzymatic catalysis. For example, the present invention provides the preparation of RNA oligonucleotides via enzymatic catalysis (also referred to as terminal transferase activity) by the controlled, template-independent addition of nucleotides to the 3'-end of an initiator oligonucleotide Methods. The addition of individual nucleotides can be repeated by a compatible polymerase (eg, poly(N) polymerase, such as poly(U) polymerase) until the desired RNA oligonucleotide sequence is synthesized. Nucleotides and polymerases useful in the methods described herein are also provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023165530-A1 |
| priorityDate |
2018-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |