abstract |
The present invention provides means for introducing nucleic acids, proteins, complexes of these, and the like into cells with excellent introduction efficiency, in particular, a method using a transduction solution. The method for transducing a molecule of interest into a cell of the present invention includes the step of contacting the cell with the molecule of interest and a solution for transduction, wherein the solution for transduction includes the following (A1) to (A5) At least one of and (B) salts: (A1) a compound represented by the following general formula (I) or a salt thereof, excluding the specified compounds; (A2) a compound represented by the following general formula (II) or its salt; (A3) nucleic acid base, etc. or its salt; (A4) the compound represented by general formula (III) or its salt, but not including malic acid; (A5) selected from creatinine, hydroxyproline, At least one or a salt thereof selected from the group consisting of 1,3-butanediol, trientine, D-cellobiose, 1,3-dimethylurea, pantolactone, and trimethyldione. |