| abstract |
The invention discloses a construction method of a hepatocellular carcinoma typing system based on an iron death process, which comprises the following steps: step one, exploring the expression condition of FRGs in HCC: first, a total of 3933 hepatocellular carcinoma samples were included from 32 datasets from GEO, TCGA and ICGC databases, respectively. The invention relates to a method for analyzing 3933 liver cancer samples which incorporate 32 data sets in total by exploring the expression condition of FRGs in HCC, identifying and verifying heterogeneous iron death subtypes, clinical states of the two subtypes, evaluating the performance of FRRS on the prediction prognosis and the curative effect of immunotherapy and developing the HCCS program package, wherein the liver cancer samples are divided into low-iron death subtypes and high-iron death subtypes and show specific functional characteristics and clinical outcome. |