http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113185599-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N37-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N37-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01P1-00 |
| filingDate | 2021-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113185599-B |
| titleOfInvention | Antibacterial peptide targeting staphylococcus aureus and preparation method and application thereof |
| abstract | The invention provides an antibacterial peptide targeting staphylococcus aureus, a preparation method and application thereof. The sequence of the antibacterial peptide F6 is shown in SEQ ID No. 1. The invention takes the 119-132 fragment of the human myeloid protein MD-2 as a basic fragment and utilizes the leucine site-directed mutagenesis technology to construct the antibacterial peptide F6 targeting gram-positive bacteria. In a minimum inhibitory concentration test and a single bacteria culture system antibacterial test, the F6 polypeptide shows extremely strong antibacterial ability against staphylococcus aureus and no gram-negative bacteria ability. In a selective sterilization test of a mixed system, F6 can preferentially kill staphylococcus aureus and has almost no influence on escherichia coli, which shows the potential of the F6 as a specific gram-positive bacteria resistant antibacterial drug and a specific gram-positive bacteria resistant polypeptide molecular probe. |
| priorityDate | 2021-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.