http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113185470-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b8fac75cc1ad7e148a37a971ea698a34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b047aad263a8f1e38efdd93ed2f36c56 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D249-12 |
| filingDate | 2021-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72850261a9f1475b0fa5a2d9e2ca3ff7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_292a6356a5348fa28c13ca19a8d50f8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5be80a48eb7cff07a704e4bbfbd2cb04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a712bdb4c5b433f498dc71fe3306f514 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_deb9d6c84a14e05b55d1a5557e92eff8 |
| publicationDate | 2021-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113185470-A |
| titleOfInvention | A kind of preparation method of prothioconazole |
| abstract | The invention relates to a preparation method of prothioconazole. In order to solve the problems of harsh reaction temperature conditions, excessive reaction steps, inconvenient amplification operation, many three wastes and low yield in the prior art, the invention provides a preparation method of prothioconazole, [1-(2-chlorine Phenyl)-2-(1-chlorocyclopropyl)-2-hydroxy]-propyl hydrazine reacts with triethyl orthoformate in an organic solvent, and then adds trimethylsilyl isothiocyanate to continue the reaction to obtain the obtained Described prothioconazole, reaction equation is: The preparation method avoids the extreme operations of low temperature, no water, no oxygen and high temperature, adopts one-pot cooking method, changes the order of feeding, reduces the yield of isomers, uses trimethylsilyl thiocyanate instead of thiocyanate, and improves the The speed of the reaction is improved, the overall yield of the reaction is greatly increased, and the cost of consumables and labor is also reduced, so that the three wastes are reduced, the time is shortened, the practical value is high, and it is suitable for industrial production and has broad application prospects. |
| priorityDate | 2021-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.