| abstract |
The invention discloses a composite nanomaterial with sterilization effect, a preparation method and application thereof. After the mesoporous nanomaterial is modified by amination, a sonosensitizer is loaded, and the surface is coated with divalent or/and ferric ions. In the presence of hydrogen oxide, the Fenton reaction occurs, and reactive oxygen species (ROS) are generated to play a bactericidal effect. By using the ultrasonic aids commonly used in oral diagnosis and treatment, the sonosensitizer can be stimulated to generate ROS, and at the same time, it can further enhance the Fenton reaction, generate a large amount of ROS, improve the efficiency of removing bacterial infection and sterilization in the root canal, and achieve the removal of bacterial biofilm in the root canal. And the purpose of completely killing bacteria. |