http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113174092-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-412 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-404 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L15-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L15-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L15-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L15-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L15-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L15-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L77-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L15-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L15-26 |
| filingDate | 2021-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113174092-B |
| titleOfInvention | Polyion complex of hyaluronic acid-ε-polylysine hydrochloride, preparation method and application |
| abstract | The invention discloses a polyion complex of hyaluronic acid-ε-polylysine hydrochloride, a preparation method and application, and belongs to the field of medical biological materials. The polyion complex of hyaluronic acid-ε-polylysine hydrochloride of the present invention has good mechanical properties, strong adhesion ability, can effectively prevent the dressing from falling off from the wound; has good self-healing ability, and the dressing is It can self-heal in a short time after rupture caused by external force; it has good antibacterial ability, and has a good inhibitory effect on gram-positive bacteria and gram-negative bacteria; it has good cytocompatibility, and electrostatic compounding avoids cross-linking agents. use. The preparation method of the present invention adopts a physical blending method, utilizes negatively charged hyaluronic acid and positively charged ε-polylysine hydrochloride to form a polyion complex through electrostatic action, has simple operation and wide raw material sources , the reaction conditions are mild, and the cytotoxicity caused by the use of cross-linking agents or the introduction of other solvents is avoided. |
| priorityDate | 2021-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.