http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113173987-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-605 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-605 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 |
| filingDate | 2021-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113173987-B |
| titleOfInvention | A kind of method for synthesizing lixisenatide |
| abstract | The invention discloses a method for synthesizing lixisenatide. For the first time, the invention adopts the side chain carboxyl group of Fmoc-Asp-OAll and amino resin coupling reaction to prepare the fragment peptide 1-28 peptide resin, and remove the 28-position Asp The α-carboxyl protecting group All is coupled with the fully protected fragment peptide 29‑44 to obtain lixisenatide. The invention can effectively improve the purity of the crude peptide, reduce the difficulty of purification, increase the yield of the final product, facilitate the large-scale industrial application of the synthesis scale, and reduce the production cost. |
| priorityDate | 2021-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 214.