http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113173939-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-09 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-025 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-02 |
| filingDate | 2021-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113173939-B |
| titleOfInvention | A kind of method for synthesizing tri-substituted alkenyl boronate by copper-catalyzed three-component reaction |
| abstract | The invention belongs to the field of organic synthesis, and in particular relates to a method for synthesizing tri-substituted alkenyl boronate by copper-catalyzed three-component reaction, and provides a stereoselective copper-catalyzed terminal alkyne, double pinacol boronate and heavyweight A method for one-pot synthesis of trisubstituted alkenyl boronate esters from nitrogen compounds or N-sulfonyl hydrazones. This method selectively difunctionalizes the end of the terminal alkyne. When using a diazo compound as a carbene precursor, a (Z)-trisubstituted alkenyl boronate is obtained with high stereoselectivity, and when an N-sulfonyl hydrazone is used, it is obtained (E)-Tri-substituted alkenyl borate. The advantages of the method of the invention are: three-component series one-pot reaction, simple operation, simple and easy-to-obtain raw materials, high reaction yield, wide substrate application range, good and controllable (E)/(Z) stereoselectivity. |
| priorityDate | 2021-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.