| abstract |
The invention relates to the field of berberine hydrochloride drug carriers, and in particular provides a berberine hydrochloride microemulsion, a preparation method thereof and its application in antibacterial drugs. The berberine hydrochloride microemulsion carrier includes RH 60, Span80, EG and PSO. Weigh RH 60, Span 80 and EG by mass, and stir and mix them at a certain temperature to form a first mixture. The first mixture and PSO are accurately weighed according to a certain weight ratio, and each component is placed in a container. Stir and mix well into the second mixture. The water phase is added dropwise to the container, and the mixture is uniformly mixed to form the third mixture, which is the target sample. The microemulsion drug carrier can play a synergistic effect with berberine hydrochloride, and can reduce the dosage of berberine hydrochloride. |