http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113166211-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5098eff6d67391cd857fae0aa3174bcb |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-885 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-80 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-80 |
| filingDate | 2019-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e407c83454a486d70d5d2c7284f71c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d097da03d33eeb507ac935d9bbf27baa |
| publicationDate | 2021-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113166211-A |
| titleOfInvention | Improved filamentous fungal host cells |
| abstract | The present invention relates to an isolated variant Ire1 polypeptide comprising (a) an amino acid substitution at position 153 in the trichoderma reesei Ire1 polypeptide of SEQ ID NO: 2; or (b) an amino acid substitution at a position corresponding to position 153 in Trichoderma reesei Ire1 of SEQ ID NO:2 and having at least 70% but less than 100% sequence identity to the amino acid sequence of SEQ ID NO: 2. The present invention also relates to a recombinant filamentous fungal host cell comprising a mutant Ire1 gene encoding the variant Ire1 polypeptide to produce a secreted heterologous polypeptide of interest, a method for producing a heterologous polypeptide of interest secreted in a recombinant filamentous fungal host cell, and a method of improving the productivity or yield of a secreted heterologous polypeptide of interest in a recombinant filamentous fungal host cell. |
| priorityDate | 2018-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1773.