| abstract |
Provided are amido bridged heterocyclic compounds having formula (I) or pharmaceutically acceptable salts, isomers, solvates, crystals or prodrugs, pharmaceutical compositions containing these compounds, and these compounds or compositions Application in pharmaceutical preparation. Such compounds and their pharmaceutically acceptable salts, isomers, solvates, crystals or prodrugs can be used for autoimmune diseases, tumors and neurodegenerative diseases related to receptor-interacting protein 1 kinase (RIPK1) treatment or prevention. |