| abstract |
The invention discloses a multi-cytokine detection chip and application thereof, the multi-cytokine detection chip comprises a report matrix, protein probe molecules and a reporter molecule with fluorescence, the protein probe molecules are fixed on the report matrix and comprise cytokines IL-1 beta, IL-18, IL-36 alpha, IL-36 beta, IL-36 gamma, IL-33, IL-5, IL-10, IL-13, TNF-alpha, IFN-gamma, IL-6, IL-4, IL-20p70 and GRO, and the reporter molecule is a cytokine standard product mixed solution with fluorescence and gradient concentration. The multi-cytokine detection chip is used for identifying and diagnosing primary immune thrombocytopenia and predicting the curative effect of glucocorticoid medicaments, can avoid glucocorticoid exposure and side effects of patients, and solves the problem that ITP specificity detection and glucocorticoid curative effect prediction are lacked in the prior art. |