| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8eba54c6ec98cca9987495619a62a634 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-20023
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-15043
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-20052
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-20022 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-867
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-165 |
| filingDate |
2021-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a97bb8df1d2e03001e72b503a2fa993
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3570b223e8e7f111a6192f02e424b23c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d96292eefc2329ef1aec0afb572110da
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a581f94fb974b56e7b526fc8084eb55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4167687e044e7b4feb573eddfa72290f |
| publicationDate |
2021-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-113151359-A |
| titleOfInvention |
Packaging system of a defective chimeric virus model of coronavirus and its application |
| abstract |
The invention discloses a packaging system of a defective chimeric virus model of coronavirus and its application. The packaging system comprises: a lentiviral envelope plasmid carrying the S gene of the MHV virus, and a plasmid carrying the E gene and the M gene of the MHV virus. Lentiviral envelope plasmids. In the present invention, the MHV virus is used to obtain a virus model similar in structure to the new coronavirus, the virus packaging process is simple, and the obtained chimeric virus has infectious activity, rather than a pseudovirus with a similar shape; and the diameter of the obtained chimeric virus particle is Similar to the new coronavirus. The virus model is characterized by a respiratory virus. The wild type can infect the lungs of mice. Similar to the new coronavirus, it can be infected through the respiratory tract. The chimeric virus model does not infect human cells and has high safety. There are fluorescent labels, and the ability to visualize the infection is strong. |
| priorityDate |
2020-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |