http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113149970-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d1b60db42a64c143f3d2b16af9f00c0e |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2021-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af63b0dc69234d654f246fe716da85fb |
publicationDate | 2021-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113149970-A |
titleOfInvention | A kind of 8-(pyridine triazole) substituted coumarin compound and its preparation method and application |
abstract | The present invention relates to a kind of 8-(pyridine triazole) substituted coumarin compound and its preparation method and application, and the structure of described 8-(pyridine triazole) substituted coumarin compound is as shown in formula (I). shown, wherein, A ring is independently selected from phenyl, naphthyl, 5-14-membered aromatic heterocyclic group. The 8-(pyridinetriazole) substituted coumarin compound involved in the present invention is a brand-new compound structure, shows good SIRT2 inhibitory activity, and has a significant protective effect on neuroma cells. Therefore, it can be widely used in the preparation of medicaments for the treatment and/or prevention of diseases or conditions related to the overactivity of SIRT2 or the overexpression of SIRT2 or the preparation of medicines for the treatment and/or prevention of Parkinson's disease, metabolic disease, tumor drug. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022183964-A1 |
priorityDate | 2021-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 150.