http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113135899-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-8679 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 |
| filingDate | 2021-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113135899-B |
| titleOfInvention | Benzocycloheptanopyridine compound, its preparation method and its use |
| abstract | The invention belongs to the field of medicine, and specifically relates to a benzocycloheptane pyridine compound, a preparation method and application thereof, and the benzocycloheptane pyridine compound has a structure of formula I or a structure of formula IV: . The preparation method includes: magnesium and N-methyl-4-chloropiperidine are heated and reacted in a first reaction solvent under the action of an initiator to obtain Grignard reagent; 8-chloro-5,6-dihydro-11H-benzo [5,6]cycloheptano[1,2-b]pyridin-11-one is reacted with the Grignard reagent in the second reaction solvent to obtain compound I and compound IV. The benzocycloheptanopyridine compound prepared by the preparation method has high purity, can realize the detection and monitoring of compound I and compound IV in the process of synthesizing loratadine, and can improve the quality of loratadine crude drug or its preparation. of great significance. |
| priorityDate | 2021-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.