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filingDate 2021-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113134114-B
titleOfInvention An anti-infection coating capable of immediate construction during surgery, its preparation method and application
abstract The present invention relates to an anti-infection coating capable of realizing instant construction during operation and its preparation method and application. The macromolecular material coating on the surface of the layer; the macromolecular material comprises chitosan and β-sodium glycerophosphate. Among them, the temperature-sensitive phase-change polymer material coating can rapidly change phase under heating conditions and cover the surface of the main structure with anti-infective drugs, realizing immediate construction during surgery, which avoids the need for pre-operative preparation in the prior art The antibacterial coating needs to consider the disadvantages of the reserve problem, and at the same time, the content of anti-infective drugs can be adjusted according to the degree of infection at the lesion during the operation to achieve personalized treatment. At the same time, the anti-infection coating has good biocompatibility, and can realize local slow-release behavior of anti-infection drugs, significantly prolonging the action time of the drugs.
priorityDate 2021-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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