http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113121549-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-582 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-34 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-34 |
| filingDate | 2019-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113121549-B |
| titleOfInvention | Method for stereoselective synthesis of chiral lactones and chiral compounds and their applications |
| abstract | The invention relates to the field of organic synthesis, and discloses a method for stereoselectively synthesizing chiral lactone, a chiral compound and its application in synthesizing biotin. The method comprises: (1) subjecting a cyclic acid anhydride, a cyclic chiral alcohol and an organic base tertiary amine to a first reaction to obtain a dicarboxylic acid monoester quaternary ammonium salt; (2) passing the dicarboxylic acid monoester quaternary ammonium salt through a Or perform a second reaction with a reducing agent without intermediate treatment to obtain an alkyd; (3) under acidic conditions, perform a third reaction on the alkyd to obtain the chiral lactone represented by formula (I). The method of the present invention can obtain the target product with high selectivity and high yield. |
| priorityDate | 2019-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 78.