http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113121537-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-10 |
| filingDate | 2021-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113121537-B |
| titleOfInvention | A kind of synthetic method of 2,8-diazaspiro[4.5]decane-8-carboxylic acid tert-butyl ester |
| abstract | The invention discloses a method for synthesizing tert-butyl 2,8-diazaspiro[4.5]decane-8-carboxylate, comprising the following steps: a first step, in a first reaction solvent, compound 1 under the action of a base React with 1-bromo-2 chloroethane to obtain compound 2; in the second step, in the second reaction solvent, compound 2 is automatically reduced by a reducing agent and undergoes a cyclization reaction to obtain compound 3. The method of the invention has the advantages of easy availability of raw materials, convenient operation, short route, high overall yield, suitability for industrial production and the like, and mainly solves the technical problem that there is no suitable industrial synthesis method at present. |
| priorityDate | 2021-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.