| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d40285e27f4ed83b8728b0d477404958 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-69
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0057 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-69
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4412
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 |
| filingDate |
2021-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b34fad94ec4c4ef45b8951ae26c7ad9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fec1eeeb1ab84afabade093a33e3aa79
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da21670852cbe0a5f6018653b6bb2cc7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_769c013fc8268d44792f16d2ffcc4d4b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c195b799e2cd808e173fe37fd0039765
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b0eea33a701391afd2853a59e3bd85b |
| publicationDate |
2021-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-113121423-A |
| titleOfInvention |
ALA hybrid 3-hydroxypyridone derivatives and preparation method and application thereof |
| abstract |
The invention designs and synthesizes a novel anti-tumor active compound with iron chelating property and photosensitivity based on the principles of rational drug design and drug-like properties. The purpose of the present invention is to provide a series of preparation methods of novel active compounds of ALA hybrid 3-hydroxypyridone (HPO) derivatives with iron ion chelating ability and PDT activity and their application in anti-tumor. A series of novel compounds with PDT activity synthesized by the present invention have significant advantages in antitumor activity. |
| priorityDate |
2021-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |