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filingDate 2021-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113121380-B
titleOfInvention A kind of preparation method of medical suture new material
abstract The invention provides a preparation method of a new medical suture material, which belongs to the technical field of biomedical materials, comprising: degumming silk through a sodium carbonate solution to obtain degummed silk; degumming silk and a shikimic acid derivative shown in formula (1) in cerium nitrate Modified silk obtained by graft copolymerization in the presence of ammonium is a new material for medical sutures. The preparation method of shikimic acid derivative shown in formula (1), under the protection of nitrogen, add shikimic acid, NMM and IBCF in tetrahydrofuran, react at 0-5 ℃, then add vigabatrin, follow the reaction by TLC, then React at room temperature, concentrate under reduced pressure, and purify by column chromatography to obtain the shikimic acid derivative shown in formula (1). The new medical suture material obtained by the preparation method of the invention has better anticoagulant properties, anti-inflammatory properties, antibacterial properties, analgesic properties, hygroscopicity, breaking strength, creep and relaxation properties and frictional force, and high suture quality.
priorityDate 2021-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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