http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113116928-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ed62447ecb838894f7d8aa53a63ca28e |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-999 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0018 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0667 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0668 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0621 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0775 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 |
| filingDate | 2020-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3179af9c2272c36e5c697fc95f00580e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e63b8f7012bf8ef6ffbed6a8a575385 |
| publicationDate | 2021-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113116928-A |
| titleOfInvention | Compositions and methods for preventing or treating eye disorders |
| abstract | The present disclosure provides a composition and method for preventing or treating eye disorders. Specifically, a method for preparing a conditioned medium of mesenchymal stem cells is provided, comprising isolating mesenchymal stem cells from an individual, maintaining the mesenchymal stem cells in a mesenchymal stem cell maintenance medium, collecting the mesenchymal stem cells for 2 to 5 passages, culturing the mesenchymal stem cells for several hours in a medium supplemented with fetal bovine serum and an adjuvant for the mesenchymal stem cell medium to obtain a conditioned medium of mesenchymal stem cells, collecting the conditioned medium, and filtering after centrifugation. The present disclosure also provides methods for preventing or treating a condition of ocular epithelial tissue, such as a dry eye condition, comprising administering the conditioned medium to an eye of an individual. The disclosure also provides pharmaceutical compositions comprising the conditioned media. |
| priorityDate | 2019-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 139.