http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113105566-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6939 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0057 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B31-125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-554 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B31-12 |
filingDate | 2021-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113105566-B |
titleOfInvention | Amphiphilic hydroxyethyl starch coupled cholesterol polymer and nano drug-loading system |
abstract | The invention provides an amphiphilic hydroxyethyl starch coupled cholesterol polymer, which is prepared by acylation reaction of carboxylated cholesterol and aminated hydroxyethyl starch, and also provides a nano drug delivery system for deep penetration of tumors and a preparation method thereof. The amphiphilic copolymer of hydroxyethyl starch coupled with cholesterol provided by the invention can be prepared into spherical nanoparticles loading indocyanine green by an ultrasonic emulsification method and a high-pressure homogenization method, and then is continuously irradiated by a near-infrared laser to prepare a sea urchin-shaped nano carrier, so that the sea urchin-shaped nano carrier is stable in structure, good in biocompatibility and good in tumor deep penetration effect. |
priorityDate | 2021-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 72.