http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113087759-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-02 |
filingDate | 2021-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113087759-B |
titleOfInvention | Synthetic method of antibacterial polypeptide derivative |
abstract | The invention relates to the technical field of polypeptide derivatives and discloses an antibacterial polypeptide derivative, wherein BOC-L-phenylalanine-poly benzyl glutamate grafted cellulose is further introduced, Boc of the BOC-L-phenylalanine is removed to generate amino in a hydrochloric acid system, the amino is subjected to addition reaction with an epoxy group of 2, 3-epoxypropyltrimethyl ammonium chloride to obtain quaternary ammonium salt-L-phenylalanine-poly benzyl glutamate grafted cellulose, cellulose grafted poly benzyl glutamate is hydrolyzed to generate carboxyl in a trifluoroacetic acid and hydrogen bromide acetic acid solution system to obtain the antibacterial polypeptide derivative, the quaternary ammonium salt has excellent antibacterial activity and antibacterial broad spectrum, L-phenylalanine-poly glutamic acid polypeptide molecules have good bioactivity and antibacterial activity, and the cellulose is subjected to graft modification, exhibit excellent antibacterial properties. |
priorityDate | 2021-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.