| abstract |
The invention provides an amorphous levamlodipine besylate, which relates to the technical field of crystal drug molecules. The X-ray powder diffraction pattern of the amorphous levamlodipine benzenesulfonate has no obvious characteristic peaks, and the whole is a steamed bread peak; its DSC scan shows that there is an endothermic peak at 108.3-113.1 °C, and a maximum endothermic peak at 110.9 °C. The amorphous levamlodipine besylate has good stability, high solubility, and is easy to dry, and the dosage form prepared by using it can increase the long-term storage safety, bioavailability, and improve drug efficacy. |