http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113072598-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ddbe8064884b45bc1eecee16c95673b9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 |
| filingDate | 2021-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb7acd275990fbbc25ffd6105288c7d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cecb83251c0c2296228be6a3500cf708 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c40f3969d99581eee1adae9efbaf2e0d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b2316ae7e12d45ec564e0938ac78886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e21e4825e3b0b3dc6fe340b521aab81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d74b1961e92c27359be56a7aeee7990b |
| publicationDate | 2021-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113072598-A |
| titleOfInvention | Method for continuously preparing emamectin benzoate and intermediate thereof |
| abstract | The invention relates to a method for continuously preparing an emamectin benzoate intermediate, and particularly discloses a method for continuously preparing a C4' -methyliminomethyl-5-allyl formate-avermectin B 1 Dissolved in an alkyl halide, with C 1‑4 Respectively pumping the alcohol into a mixer for mixing, respectively pumping the alcohol and a reducing agent solution into a microchannel modular reaction device, controlling the reaction temperature to be-15-25 ℃ and the reaction residence time to be 3-50 s to obtain C4' -methylamino-5-allyl formate-abamectin B 1 (ii) a The invention also discloses a method for continuously preparing the emamectin benzoate. According to the technical scheme, the modularized microchannel reaction device is adopted, so that continuous production operation can be realized, and the stability of product quality is greatly improved; dichloromethane is adopted as a solvent in all reaction steps, the front and the back are unified, and the cross mixing of the solvents cannot be generated; greatly improved mass and heat transfer capacity, reaction separationThe selectivity is improved, side reactions are reduced, the yield is improved, the reaction rate is effectively accelerated, and the reaction time is shortened. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114805145-A |
| priorityDate | 2021-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.