http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113061259-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G83-008 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G83-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 |
| filingDate | 2021-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113061259-B |
| titleOfInvention | Preparation method of metal organic framework material for treating cerebral arterial thrombosis |
| abstract | The invention discloses a preparation method of a metal organic framework material for treating ischemic stroke, which comprises the following steps: step 1, preparing a metal organic framework material; step 2, removing unreacted raw materials and solvent molecules in the metal organic framework material, and activating the metal organic framework material; and 3, carrying out dopamine modification on the obtained metal organic framework material. The superoxide dismutase (SOD) of the metal organic framework material can effectively convert oxygen free radicals into water and oxygen, and simultaneously, the novel metal organic framework material can up-regulate the activity of endogenous antioxidase of nerve cells, thereby further realizing the removal of the free radicals. The metal organic framework material is delivered in a lateral ventricle injection mode in a stroke mouse, so that the focus microenvironment is improved, the nerve cell death rate is reduced, the infarct volume is reduced, and the post-operation behavioural function of the mouse is effectively recovered. |
| priorityDate | 2021-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 137.