http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113057939-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-42 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-56 |
| filingDate | 2021-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113057939-B |
| titleOfInvention | A kind of preparation method and application of triptolide drug coated with chemically modified gelatin micelle |
| abstract | The invention relates to a preparation method and application of a chemically modified gelatin micelle-coated triptolide drug, which comprises nano-micelles and triptolide drugs encapsulated in nano-micelles; The bundle is an oleic acid-gelatin amphiphilic molecule obtained by covalent action of amide bond between oleic acid and gelatin, or a phenylboronic acid-oleic acid-gelatin amphiphilic molecule obtained by covalent action of substituted phenylboronic acid, oleic acid and gelatin with amide bond. . Compared with the existing triptolide preparation technology, the present invention adopts novel nano micelles to encapsulate the triptolide, which solves the problem that the solubility of triptolide in water is small and it is difficult to prepare a solution-type preparation; and the triptolide The nanometer size of the micelles makes triptolide easier for effective transdermal administration, which is beneficial to improve the bioavailability. |
| priorityDate | 2021-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.