abstract |
The invention provides a pyridone derivative and application thereof in preparing a medicament for preventing and/or treating tuberculosis caused by mycobacterium tuberculosis, belonging to the field of pharmacy. The structure of the pyridone derivative is shown as a formula (I). Experimental results show that the pyridone derivative provided by the invention can specifically inhibit the activity of mycobacterium tuberculosis, has small toxic and side effects, can be used for preparing a medicament for resisting mycobacterium tuberculosis and preventing and/or treating tuberculosis, and provides a new choice for medicaments for treating tuberculosis (particularly drug-resistant tuberculosis). |