http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113045398-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b69a8b4cf6c8fa0ebd23683dbec7837d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D53-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J19-0066 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J19-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C221-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D53-78 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J19-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D53-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-825 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D53-40 |
| filingDate | 2021-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06212a6b5975879d7383973ef72ee740 |
| publicationDate | 2021-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113045398-A |
| titleOfInvention | A kind of preparation technology of 5-fluoro-2-hydroxyacetophenone |
| abstract | The invention relates to the technical field of chemical synthesis, in particular to a process for preparing 5-fluoro-2-hydroxyacetophenone, comprising the following steps: step 1, preparing 4-acetamidophenol acetate from aminophenol, acetic anhydride and benzene; step 2. Anhydrous aluminium trichloride, sodium chloride and the 4-acetamidophenol acetate obtained in step 1 are thrown into the stirring device to prepare 2-acetyl-4-acetamidophenol; Step 3, hydrochloric acid, The 2-acetyl-4-acetamidophenol obtained in step 2 is refluxed, cooled, adjusted to pH 6-7, solid is precipitated, and dried to prepare 2-acetyl-4-aminobenzene; 2-acetyl-4-aminophenol was added to excess hydrogen fluoride to prepare 5-fluoro-2-hydroxyacetophenone. The beneficial effects are as follows: compared with the two-step reaction in the prior art, the trivial separation and purification of the intermediate product ester is eliminated, the reaction time is greatly shortened, the operation is simple, and the method is suitable for industrial production. |
| priorityDate | 2021-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.