http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113025729-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b4711b7defc1422cdb7f86d2c95657bf |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-689 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-32 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-689 |
| filingDate | 2020-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33d71bd98448da1829c9818ede0edb2a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02b9eb07f6761b427eac7925179292de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38cbec585de55a9ffb955e29c28dca6b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86a07f336ff1653f8ae48550043645a7 |
| publicationDate | 2021-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113025729-A |
| titleOfInvention | Gene mutation sites related to aminosalicylic acid resistance in Mycobacterium tuberculosis and its application |
| abstract | The invention provides a gene mutation site related to the drug resistance of Mycobacterium tuberculosis to aminosalicylic acid (PAS) and its application. The gene mutation site is metH gene mutation site and/or rv3253c gene promoter region mutation site ; Relative to the nucleic acid sequence of SEQ ID No.1, the metH gene mutation site and its mutation type are A1108G, T1631C or A3292C; relative to the nucleic acid sequence of SEQ ID No.2, the rv3253c gene promoter region The mutation site and its mutation type are G7A, C31T, C33T, G35A, T39C, G40A, G42A or G57A. The mutation on the promoter region of the metH gene or the rv3253c gene provided by the present invention will lead to an increase in the level of PAS drug resistance of Mycobacterium tuberculosis, so the gene mutation site related to the drug resistance of Mycobacterium tuberculosis provided by the present invention can be used as a detection target It can effectively shorten the diagnosis time of the corresponding patients and save the treatment time and cost of the patients. |
| priorityDate | 2020-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.