http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113024783-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G2230-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G63-664 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G63-78 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G63-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G63-664 |
filingDate | 2021-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2023-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2023-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113024783-B |
titleOfInvention | A kind of synthetic method of degradable block copolymer hydrogel |
abstract | The invention belongs to the field of biomedicine and chemical industry, and in particular relates to a synthesis method of a degradable block copolymer hydrogel. The present invention is formed by copolymerizing ε-caprolactone and polyethylene glycol as raw materials, and its specific steps are: weighing ε-caprolactone and polyethylene glycol, pretreatment with molecular sieves to remove water, and adding them to the reactor, Add catalyst, under nitrogen protection, react at 100-150°C for 2-6 hours to obtain crude product of PCL-PEG-PCL block copolymer; the crude product is dissolved, precipitated and dried to obtain PCL-PEG-PCL degradable block copolymer Hydrogels. The hydrogel not only has biocompatibility and degradability, and the gel phase transition temperature (LCST) is within the body temperature range of the human body, and the source of the raw materials used is easy to obtain, the price is low, and the synthesis method is simple and feasible. |
priorityDate | 2021-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.