http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113024730-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-412 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-414 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-06 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F251-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3852 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3847 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3817 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3821 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3834 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F251-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-20 |
| filingDate | 2021-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113024730-B |
| titleOfInvention | Preparation and use methods of injectable composite chitosan hydrogel for bone repair |
| abstract | The invention relates to a preparation method and a use method of injectable composite chitosan hydrogel for bone repair, wherein the hydrogel mainly comprises modified chitosan, an internal carrier cell and a cell growth promoting factor. Firstly, preparing a hydrogel precursor solution through emulsion polymerization, wherein the main component of the hydrogel precursor solution is chitosan macromolecules grafted and modified by poly N-isopropylacrylamide, and the hydrogel can be in a solution state at room temperature and can realize rapid gelation at the physiological temperature environment of a human body. By mixing with the cell suspension and the cell growth promoting factor, the obtained composite solution can realize in-situ rapid gelation at the damaged part of the bone tissue, realize in-situ fixation of cells, not only provide good support for the damaged part, but also promote adhesion, proliferation and differentiation of cells in the damaged part. The hydrogel has the advantages of simple preparation, convenient use, rapid response and good biocompatibility, and can be used in various biomedical related fields such as tissue repair, drug controlled release, cell culture, cancer treatment and the like. |
| priorityDate | 2021-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.