http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113024573-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-443 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-405 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-381 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2019-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113024573-B |
titleOfInvention | Epodophyllotoxin derivative, preparation method and application thereof in preparation of antitumor drugs |
abstract | The invention discloses an epipodophyllotoxin derivative, which has a structure shown in a general formula I: wherein R is substituted or unsubstituted C4-C15 aryl, substituted or unsubstituted C2-C15 heteroaryl, substituted or unsubstituted C6-C15 fused aryl, and substituted or unsubstituted C4-C-15 fused heteroaryl. Experiments prove that the epipodophyllotoxin derivative disclosed by the invention has good tumor inhibition activity, can be used as an anti-tumor medicament, and is effective on diseases such as leukemia, liver cancer, lung cancer and the like. |
priorityDate | 2019-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 103.