Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff9a8a894ec90fe1c7e5ad02149075d3 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
2021-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e121995c27eec8e0d0c2a1508f7bdeca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d75f6d5a6cf85e6e052c952777249c6d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38f96622542d5b4c71ede851d350640d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36433a0d54a2f4cf45954a338caea5ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e175ccfb645230095b05cdbb76e01eec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_654c7a0a792094f0a9fd2df8a227b743 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d415fbbfc5830dc9f37561ff3d018f79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c7f536a7d4a3176bdcc49aa143a2ad6 |
publicationDate |
2021-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-113024557-A |
titleOfInvention |
A kind of Peganumine A alkaloid structure simplification and its application |
abstract |
The invention discloses a simplification of Peganumine A alkaloid structure, a stereoisomer or a medicinal salt thereof, and the structure is shown in the following general formula: The definition of each substituent is detailed in the specification. The structural simplification of Peganumine A alkaloids provided by the present invention has obvious inhibitory effect on the proliferation of liver cancer HepG2, lung cancer A549 and colorectal cancer HCT116, and the anti-tumor activity of some compounds is stronger than the anti-liver cancer HepG2 activity of Peganumine A reported in the literature . |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114933599-A |
priorityDate |
2021-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |