| abstract |
The invention discloses a biological ink based on a phenylboronic acid copolymer immobilizing particle gel, an application and a preparation method. The bio-ink contains two components, the first component is particle gel, the second component is a copolymer hydrogel system formed by boron ester bonds, the first component is mixed by the first component The two components were immobilized to form a shear-thinning, self-healing bioink. The bioink prepared by the invention not only has the characteristics of shear thinning, self-healing, good biocompatibility, etc., but also improves the loading density of biologically active substances, prevents the shear damage of microorganisms, and increases the specific surface area. And the mass transfer rate makes the bioink prepared by this method have extremely broad application prospects in the fields of 3D printing biocatalysts, biological living materials, wearable flexible electronic sensor devices, soft robots, biomedicine and other fields. |